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TSPAN2 encodes a four transmembrane protein in cells which mediates signal transduction and is involved in the modulation of development, activation, growth, and movement of cells [16].
Using this RNAi-compatible OP50 strain and the other bacterial strain HT115, we feed worms different diets while delivering RNAi to interrogate the genetic basis underlying diet-dependent differential modulation of development, metabolism, behavior, and aging.
Broader effects on leukocyte function have now emerged including altered adhesion molecule expression, cytokine and chemokine release and modulation of development of adaptive immune responses via altered MHC class II upregulation.
R2R3-MYB genes are involved in various plant-specific processes such as regulation of secondary metabolism, modulation of development, determination of cell fate and identity and responses to environmental factors and hormone.
The complexity of the interplay between environmentally sensitive epigenetic markers in sperm and epigenetic modulation of development in the following generation is further illustrated by a recently published report on the transgenerational consequence of paternal exposure to a conditioning olfactory experience [ 175].
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Our results indicate that HDAC1 plays an important role in chondrogenesis and may represent a therapeutic target for modulation of cartilage development.
In the CNS, adenosine has multiple functions, such as modulation of neural development, neuron and glial signalling and the control of innate and adaptive immune systems.
The modulation of muscle development processes is triggered by sequential events of gene activation and inhibition.
Future investigations to determine the precise mechanism by which LOV1 acts in two intersecting pathways will provide a better understanding of the modulation of reproductive development in plants under continuously changing temperature conditions.
These studies therefore shed light on a conserved pathway in the modulation of tissue development.
B, Down-regulAted genes after shading.
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