These results indicate that vascular tone is modulated by subtle changes of EC [Ca2+]i level, which seems to serve as an integrating signal in both basal and stimulated states.
Analysis of inactive DrEndoIII2 (K132A/doubledouble mutant) interacting with undamaged DNA, and the active enzyme interacting with damaged DNA also indicate that the electron transfer is modulated by subtle differences in the protein-DNA complex.
The action of antifungal agents is modulated by subtle modification of the membrane lipid composition [17].
Since our mouse studies revealed aggressive social behavior as a central phenotype modulated by subtle Mecp2 overexpression, we started a hypothesis-driven analysis on subjects of the GRAS Göttingen Research Association for Schizophreniaa) data collection (Ribbe et al, 2010).
Such traits are not inherited in a monogenic mendelian fashion, but are expected to be caused or modulated by subtle differences in multiple different types of regulation, including miRNA-mediated regulation.
Neuroimaging studies have shown how adults' brain activation is modulated by subtle manipulations of word frequency, semantic content, and visual complexity (Indefrey and Levelt 2004; Price et al. 2005; Graves et al. 2007; Wilson et al. 2009; Indefrey 2011; Price 2012).
