Sentence examples for modulated by several from inspiring English sources

Because Ehd1 is modulated by several regulators, it acts as a mediator of various floral signals.

Stem cell differentiation is modulated by several key molecules, including cytokines, hormones, and engineered peptides.

The response to the neurotransmitter binding can be modulated by several chemical compounds acting at topographically distinct sites, as documented by a large body of literature.

Importantly, the developmental trajectory of brain changes is not uniform and may be modulated by several factors such as onset of disease mechanisms, risk-associated and protective genes, converging comorbidity, and individual brain reserve.

This proteolytic activity of the aggrecanases can be modulated by several means, including altered expression, activation by proteolytic cleavage at a furin-sensitive site, binding to the aggrecan substrate through the C-terminal thrombospondin motif, activation through post-translational processing of a portion of the C-terminus and inhibition of activity by the endogenous inhibitor TIMP-3.

These main effects were modulated by several interactions.

In addition, the degree of rate variation across sites was modulated by using several values of α, the shape parameter of the gamma distribution.

Particularly, HNF4α expression, which has been shown to be regulated by HNF1α [ 20, 21], was decreased early after transfection and this decrease was strongly correlated to HNF1α expression, which was modulated by using several concentrations of siRNA (Additional files 2A and 2B).

Expression analysis pointed to a down-regulation of NF- kB, the final actor of a complex pathway of signal transduction finely modulated by ubiquitination at several levels [ 94].

As NF- kB signalling is deeply modulated by ubiquitination at several levels [ 94, 95], further studies on the regulation of NF- kB by ubiquitination in DS may add new clues to the pathogenesis of DS.

Moreover, a Pubmed search using the query "gene name AND aging [title/abstract]" gave some interesting hints, as the expression of CACNA1G, COL1A1, LAG3, PTGDS and ZEB2 genes resulted modulated by age in several models [ 32– 32].