Sentence examples for modulated by post-translational from inspiring English sources
Dynamic chromatin structure is modulated by post-translational modifications on histones, such as acetylation, phosphorylation and methylation.
Notably, both the primary and secondary feedback loops are modulated by post-translational modifications in versatile ways, e.g, protein ubiquitination, phosphorylation/dephosphorylation, acetylation/deacetylation, poly ADP-ribosylation and O-GlcNAcylation (Reddy and Rey, 2014).
Importantly, HMGB1 extracellular activity is modulated by post-translational modifications.
KATP channels are modulated by post-translational mechanisms, such as protein phosphorylation mediated by cAMP-dependent protein kinase (PKA) [13] [15], Ca2+/phospholipid-dependent protein kinase (PKC) [16] [20], and extracellular signal-regulated kinase (ERK) [21].
The disagreement observed between Mn-SOD protein content and its activity in the AO adults is intriguing and suggests that Mn-SOD activity may be modulated by post-translational modification [66].
However, we are aware that the levels of individual proteins may not always reflect mRNA levels, and that the activity of certain proteins, and therefore the activation state of cellular pathways, can be further modulated by post-translational modifications.
In eukaryotes, the activity of many components of the translational machinery is modulated by various post-translational modifications in order to adjust either global or mRNA-specific translation.
The transcriptional activity of FoxO3a is modulated by its various post-translational modifications.
Moreover, it is also possible that PABP1 poly(A) binding and/or these PABC interactions are modulated by PABP1 PTMs (post-translational modifications).
The enzyme peptidyl-prolyl cis/trans isomerase NIMA-interacting-1, Pin1, has been shown to modulate the activity of p53 and p73 by post-translational modifications (32– 32).
One cycle involving both loops takes about 24 hours to be completed and is governed by post-translational modifications and may be modulated by the actions of nuclear receptor co-activators and co-repressors.
