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Transcriptional regulation of genes is modulated by histone modifications, DNA methylation, and non-coding RNA binding [18].
A growing body of data indicates that gene silencing is also modulated by histone deacetylation, an epigenetic mechanism different from methylation [22].
Here we propose that co-transcriptional recruitment of splicing factor is modulated by histone modifications and Pol II processivity, which provides a link between chromatin modifications, transcription and splicing.
Other studies, however, have shown that metallothionein gene expression can be modulated by histone modifiers [ 44].
Our data also reveal that origin structure is dynamic and can be locally modulated by histone deacetylation, as well as by origin activation.
BR-F colonies (but not BR-RF colonies) express genes located in HAST domains, i.e., regions in the genome whose expression is modulated by histone deacetylase Hda1p [ 22].
Similar(52)
Baxter et al. emphasized on the transcriptional activity of HIF-α modulated by the histone methyltransferase G9a mediated methylation of non-histone proteins such as Reptin and Pontin in hypoxia.
Although hormones and downstream transcription factors are considered main drivers directing mammary gland development and oncogenic transformation, an emerging body of evidence suggests these processes are modulated by dynamic histone methylation landscapes.
The binding of MOZ/MORF complexes to specific genomic regions and their activity are modulated by posttranslational histone modifications.
These findings suggested that Cyc8 Tup1 repression activity is modulated by changes in histone acetylation.
Activity of VDR can be modulated epigenetically by histone acetylation.
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altered by histone
changed by histone
targeted by histone
regulated by histone
modified by histone
modulated by change
modulated by phonology
modulated by emotion
modulated by performance
modulated by respiration
modulated by dopamine
modulated by degree
modulated by cell
modulated by doping
modulated by color
modulated by task
modulated by block
modulated by hypothermia
modulated by morph
modulated by protein
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