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Amyloid-ß production via cleavage of amyloid-ß protein precursor is modulated by cell density.
Aggregation efficiency (S) was found to be modulated by cell seeding density, microcarrier concentration, addition of Vc and agitating speed.
For successful delivery, the viruses should have high infectious ability to CIK cells, and the replication of viruses should be strictly modulated by cell vehicles.
Macrophages are activated and modulated by cell debris and molecules bearing the damage-associated molecular patterns (DAMPs) released by injured cells, and by cytokines present in the specific immuno-microenvironment during CKD (Williams et al., 2010).
If such covalent modifications occur, however, it is difficult to envision how they are modulated by cell signaling.
The production of BDNF by normal B and T lymphocytes is also modulated by cell activation [4], [33].
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Our recent study of basonuclin suggests that rRNA transcription is modulated by cell-type-specific factors [23] [25].
However, among the analyzed proteases, only MMP-2 expression was significantly modulated by cell-ECM elements interaction.
Furthermore, the expression of all MMP inhibitors was modulated by cell-Matrigel contact only in highly invasive and metastatic cell lines.
The expression of all analyzed MMP inhibitors was modulated by cell-Matrigel contact in highly invasive and metastatic cell lines (MDA-MB-231 and Hs578T) (Fig. 1B).
Moreover, Notch signaling which can be modulated by cell-associated and soluble ligands has been shown to be crucial for the maintenance of satellite cell quiescence 47, 48.
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