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In the following experiments our objective was to modulate the signalling pathways that may be involved in the interpretation of the signal while avoiding interference with the production of the signal, as this would likely also affect normal germ layer formation and patterning of the embryonic axes with the potential to influence cardiogenesis indirectly.
Autoregulation of BMP ligand or antagonist expression is one possibility to modulate the signalling pathway endogenously.
Bacterial factors, however, are also able to modulate the signalling pathways of their host cells and thus modify the resulting immune response.
Although TfR2 is a minor contributor to the uptake of transferrin-bound iron by the liver, experiments with mice have shown that its major role is to modulate the signalling pathway that controls Hamp induction [ 34].
They also found a decrease in uEVs of miRNA-155 and miRNA-424 that are expressed on podocytes and that negatively modulate the signalling of angiotensin II, TGF-β1 and vascular endothelial growth factor.
For example, DCIR contains an ITIM in its cytoplasmic tail which recruits tyrosine phosphatases (SHP-1 and SHP-2) following ligand binding to modulate the signalling pathways induced by other PRRs, such as inhibition of TLR8-or TLR9-induced cytokine production (Geijtenbeek and Gringhuis, 2009).
Similar(53)
The square-wave generator is used at 20 kHz to modulate the signal generator at 100% AM modulation.
We apply BPSK to modulate the signals.
BFSK is used to modulate the signals at both the source and the relays.
It has also been found that the nanoparticles can modulate the signal transduction in bacteria.
Oxidative stress has been reported to modulate the signal transduction pathways in lymphocytes [17].
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modulate the bone
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modulate the anger
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modulate the histone
modulate the host
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