Our findings suggest that the biotrophic pathogen can use the plant-like hormone to modulate the host cellular environment and in particular host metabolism and that such modulations weaken host defence.
But they rarely modulate the host to repair and regenerate neotissues (Chan and Mooney, 2008).
Moreover, it is secreted by the intracellular parasite Leishmania to modulate the host response.
Preliminary data also suggested the ability of HCcAg to efficiently enhance and modulate the host immune response against HBsAg.
Statins have been reported to modulate the host response in controlled models of human inflammation induced by intravenous or intrabronchial administration of lipopolysaccharide (LPS).
We postulate possibilities to utilize biomaterial physicochemical modifications to modulate the host inflammatory response and develop strategies for effective biomaterial integration.
Thus, the aim is to use the vaccine to deliver the antigen in a different way to modulate the host immune response.
Alternatively, engineered CRISPR Cas systems can be harnessed to genetically modify probiotics and enhance their therapeutic potential to deliver vaccines or modulate the host immune response.
Emerging evidence suggests that S. aureus, in addition to inducing a pro-inflammatory response, may have the capacity to modulate the host immune system.
Different viruses use different strategies to do this, and consequently, the therapeutic vaccine should be designed to remedy, correct, or at least partially modulate the host immune response in a more antiviral direction.
Further we explore the utility of different bioactive agents including peptides, carbohydrates and proteins which can be conjugated the polymer brush to make the surface actively interact with the body and modulate the host response.
