Sentence examples for modifies chromatin structure from inspiring English sources

For example, subtle genetic mutations in CBP may be amplified if a person has a specific environmental exposure to an agent that modifies chromatin structure.

From these results it was concluded that FOXA and HNF1 proteins are critical regulators of HNF6 expression and that binding of FOXA2 modifies chromatin structure to permit access of other transcription factors, as detailed in the study of Cirillo et al. [19].

HMGN1 protein binds to nucleosome and modifies chromatin structure.

Histone lysine methylation modifies chromatin structure and regulates eukaryotic gene transcription and a variety of developmental and physiological processes.

Acetylation of histones by these factors modifies chromatin structure and provides a more accessible promoter environment for recruitment of components of the general transcriptional machinery [ 22].

Several models have been postulated to explain how SWI/SNF modifies chromatin structure, especially the ATP-dependent mobilization of nucleosomes in cis along the DNA and the ejection and insertion of histone octamers [62].

HDAC2 is a histone deacetylase that modifies chromatin structures and represses transcription.

In this review, we analyze how these elements modify chromatin structure in a hierarchical manner by acting on the nuclear machinery.

The cellular response to N-activation was analysed under several conditions known to modify chromatin structure packaging.

Regarding HATs, they regulate gene expression by catalyzing acetylation of the N-terminal region of histones, thereby modifying chromatin structure in a manner that facilitates transcriptional activation [18].

Transcriptional control during the pluripotent state is applied by the polycomb group (PcG) of proteins that work to modify chromatin structure.