The phrase "alter chromatin structure" is correct and usable in written English.
It can be used in scientific contexts, particularly in discussions related to genetics, molecular biology, or biochemistry, where changes to chromatin affect gene expression and cellular function.
Example: "Certain environmental factors can alter chromatin structure, leading to changes in gene expression that may impact cellular behavior."
Alternatives: "modify chromatin configuration" or "change chromatin arrangement."
The development of cancer is closely associated with the stepwise accumulation of not only somatic mutations, but also epigenetic alterations that alter chromatin structure and lead to dysregulated gene expression.
Therefore, mechanisms that alter chromatin structure play an essential role in gene regulation.
These modifications alter chromatin structure through noncovalent interactions within and between nucleosomes, leading to changes in macromolecular organization and promoter accessibility.
Epigenetic marks must be erased and re-written to alter chromatin structure and gene expression patterns during reprogramming as the fibroblast signature is repressed and a cardiomyocyte gene expression program is activated.
Our results strongly suggest that glycation of important nuclear protein targets such as histone H1 occurs in vivo and that these oxidative changes may alter chromatin structure, ultimately contributing to chronic changes associated with aging and diseases such as diabetes.
Many ATP-dependent enzymes alter chromatin structure during gene transcription and other processes involving DNA [26].
Chromatin remodelling enzymes are ATP-driven motor proteins that act to alter chromatin structure and accessibility.
Nucleosome remodellers alter chromatin structure by shifting nucleosomes from one position to another along the DNA (nucleosome sliding) [2].
Acetylation and deacetylation of histones by histone acetyltransferases and histone deacetylases (HDACs) alter chromatin structure in a way which dynamically affects transcriptional regulation [30], [31].
This family of proteins helps alter chromatin structure and enhances transcription [45] and may also have functional relationship to regulation of GnRH release.
Many of these co-regulators are enzymes that alter chromatin structure or control sequential transcriptional reactions [1], [7], which include ATP-dependent chromatin remodeling complexes (SWI/SNF) [8].
