Sentence examples for modulates chromatin structure from inspiring English sources

Set2-catalysed H3K36me modulates chromatin structure via activation of the Rpd3S histone deacetylase complex5,11,12,13, antagonizing the function of Asf1 (ref. 15) and regulating ISW1b functISW1b.

These data support a model in which ATRX loss modulates chromatin structure primarily in the immediate vicinity of its vacant binding sites, dysregulating local gene expression and inducing glioma-relevant phenotypes (Fig. 9).

The methylation of lysine residues on histone proteins modulates chromatin structure and thereby contributes to the regulation of DNA-based nuclear processes such as transcription, replication and repair.

How TORC1 modulates chromatin structure to control gene expression, however, is largely unknown.

The deposition of such PTMs modulates chromatin structure, which directly affects the abovementioned DNA-related events [ 3, 4].

Methylation does not interfere only in transcription factor binding activity, but also modulates chromatin structure by modifying the interaction between core histones and DNA.

As a histone deacetylase (HDAC), Rpd3 modulates chromatin structures, including the heterochromatin of Drosophila telomeres, by interacting with several chromatin remodeling complexes [ 1].

Thus the qPCR assay highlights two separate mechanisms for TSA to enhance the luciferase signal of the DMD minigene construct – one as a general effecter of gene transcription by modulating chromatin structure, and another as a modulator of pre-mRNA splicing.

Enzymes involved in deacetylation of histones, thereby modulating chromatin structure.

Our data provide a temporal picture of how Set2 and H3K36me might modulate chromatin structure after a DSB.

Metabolic regulation of histone marks is associated with diverse biological processes through dynamically modulating chromatin structure and functions.