Because conducting these studies is so tricky, their findings are regularly overturned or modified by further research.
To the Editor: Peter Pitts warns that a proposed Center for Comparative Effectiveness to test new drugs would be dangerous because "conducting these studies is so tricky, their findings are regularly overturned or modified by further research".
(Angsupanich and Ledward1998) suggested that the denaturation of myosin alone gave rise to the new transition which was not modified by further denaturation of sarcoplasmic protein, connective tissue, and actin.
Of importance, DNA methylation patterns established around implantation can be modified by further methylation or demethylation during subsequent stages of organogenesis [5].
As the interview progresses, these initial typifications become more specific and nuanced, modified by further interactions with the patient [ 60].
The association between pre-hospital management and 30-day mortality was not modified by further adjustment for the hospital of first admission (OR: 0.55, 95% CI: 0.31 to 0.98, P = 0.043).
