Sentence examples for modified by alternative from inspiring English sources

Surprisingly, CbmNav1.5 was substantially modified by alternative splicing as well, resulting in two alternative splicing variants having significant deletion at functionally important regions of the channel: to have seven amino acid residues substitution at DI S3 S4 extracellular loop were found in CbmNav1.5b.

Together these data with T1620Ka and T1620Kc suggested that the positively charged lysine at position 1620 has a dominant effect on channel gating, independently of whether or not the intracellularly located DII-DIII linker is modified by alternative splicing (Fig. 1A).

Therefore, we examined whether PCB 28 could have been modified by alternative sources of exposure.

The same approach can be extended to the remaining sites modified by alternative splicing (AS1, 2, 5).

The position of peptides within the overall domain structure of neurexin proteins is indicated (laminin-G and EGF-domains are marked, transmembrane domain (TMD) shown as box, sites modified by alternative splicing in blue).

Since the N terminus is the only domain modified by alternative splicing and subject to diversifying selection, but the DNA binding domains are not, rapidly evolving centromere sequences are unlikely to be the primary driver of CenH3 sequence diversification.

This mechanism perhaps can be modified by the alternative cleavage of phospho-T59 Bid to jBid at some conditions.

When blood is lacking or is modified by postmortem factors, alternative matrices may be useful.

Genetically engineered strains of mice, modified by gene targeting (knockouts), are increasingly being employed as alternative effective research tools in elucidating the genetic basis of human deafness.

Moreover, subsets of memory PCs may reside in alternative niches [ 14, 15], which might be differently modified by therapeutic treatments [ 16].

An alternative method of acid-base evaluation has been proposed by Stewart [ 3] and was later modified by Figge et al. [ 4– 6].