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According to this model, the presence of such deamidation-susceptible Asn may account for the occurrence of time-dependent structural modifications of functional meaning.
Our approach is motivated by results from systems biology where it has been demonstrated that the comparison of networks representing molecular pathways allows to study important modifications of functional units due to pathogenesis [24], [25].
The field of pharmacoproteomics may be more important than the pharmacogenetics of individual patients as it represents the effects of post-translational modifications of functional proteins which are responsible for the phenotypic effects and may serve as important biomarkers in patients.
Protein posttranslational modifications (PTMs) indicate addition, subtraction, and/or modifications of functional groups [ 29, 30].
These variations in chromatin structure result in changes in transcription in numerous sorts of biological processes and provide enormous modifications of functional responsiveness.
Dramatic evolutionary modifications of functional V gene germline repertoires are assumed to reflect selective pressures exerted on the adaptive immune system and in turn result in beneficial changes in the expressed TR repertoires.
Similar(54)
The results were graded on a modification of functional grading system given in the literature [1].
For templated sol gel synthesis, three types of β-cyclodextrin-containing organosilanes were prepared by modification of functional silane with oligosaccharide using N,N′-carbonyldiimidazole as linking agent.
Demineralization of the coal was carried out with different concentration of the leachant to understand its effect on grain size, stacking and modification of functional group.
It is a linear polysaccharide consisting of N-acetyl-glucosamine (acetylated) and glucosamine (deacetylated) repeating units, and its abundant reactive groups facilitate chemical modification of functional groups.
The resulting INP solutions (or inks) can be used for the tailored modification of functional surfaces of electrochemical devices such as, for example, sensors.
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