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In this study, we show that the efficacy of B-13 in vitro as well as in intact cells can be enhanced by suitable modification of functional groups.
The successful methods to maximize photocatalytic activity of H2 production from water by introducing light sensitization and anchoring catalytic sites within MOFs, tuning the band gap of MOFs by modification of functional groups were also highlighted.
Since more than half century ion beams are used for modification of functional properties of various materials: after semiconductors, metals and ceramics ion irradiation appeared recently as an interesting method of modification of organic materials, especially for friction and wear properties.
Imprint lithography is emerging as an alternative nano-patterning technology to traditional photolithography that permits the fabrication of 2D and 3D structures with <100 nm resolution, patterning and modification of functional materials other than photoresist and is low cost, with operational ease for use in developing bio-devices.
The results were graded on a modification of functional grading system given in the literature [1].
For templated sol gel synthesis, three types of β-cyclodextrin-containing organosilanes were prepared by modification of functional silane with oligosaccharide using N,N′-carbonyldiimidazole as linking agent.
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According to this model, the presence of such deamidation-susceptible Asn may account for the occurrence of time-dependent structural modifications of functional meaning.
Our approach is motivated by results from systems biology where it has been demonstrated that the comparison of networks representing molecular pathways allows to study important modifications of functional units due to pathogenesis [24], [25].
The field of pharmacoproteomics may be more important than the pharmacogenetics of individual patients as it represents the effects of post-translational modifications of functional proteins which are responsible for the phenotypic effects and may serve as important biomarkers in patients.
Protein posttranslational modifications (PTMs) indicate addition, subtraction, and/or modifications of functional groups [ 29, 30].
These variations in chromatin structure result in changes in transcription in numerous sorts of biological processes and provide enormous modifications of functional responsiveness.
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