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In this study, these two sites were chosen to determine whether methylation might directly interfere with transcription factor binding and promoter activity.
Alternatively, the exposure of potential effector CTLs to PRN might directly interfere with CTL proliferation and/or effector function.
There is evidence to indicate that ruthenium compounds might directly interfere with specific proteins involved in the signal transduction pathways, cell adhesion and migration processes [ 21- 23].
The specific mechanism by which the BAT domain blocks telomerase elongation is not clear; it might directly interfere with the catalytic subunit Est2 recruitment or it could affect elongation indirectly by altering telomere processing or C-strand synthesis.
In order to exclude a possible trivial explanation that MG-132 might directly interfere with DNA-PK activity, lysates of PC-3 cells were incubated with MG-132 and studied for p53 phosphorylation.
From our array data, a large group of genes related to photosynthesis were identified as strongly repressed by NAA in the FAZ at an early stage, implying that NAA might directly interfere with photosynthesis.
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Cameron might argue he wouldn't directly interfere, but what of the future?
That site might overlap with the Sp1 site and thus directly interfere with the Sp1 transcription factor.
Shielded by the plasma membrane, drugs with extracellular targets might cause less side effects as they can less directly interfere with intracellular signaling 15– 215
One can further speculate that these drugs might have less side effects as they will not directly interfere with intracellular signaling events 73, but are expected to regulate primarily outside-in cell signaling.
Putin's government does not directly interfere with research or publications about the Communist repressions.
More suggestions(15)
might directly impair
might directly stimulate
might directly modulate
might directly detract
might directly create
might directly support
might directly alter
might directly decrease
might directly interact
might directly phosphorylate
might directly harm
might directly promote
might directly serve
might directly target
might directly compete
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