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FGF2, which is expressed ubiquitously in mesodermal and neuroectodermal cells, has various physiological functions.
Pitx2 is important for mesodermal and neuroectodermal development in vivo [ 33].
We examined CD133 expression in endodermal, mesodermal and neuroectodermal organs of adult humans.
It would seem that these mesodermal and neuroectodermal epithelial tumors may display class behavior independent of their epithelial morphology.
It has been shown that Notch signaling influences the cell fate decision between mesodermal and neuroectodermal cell fates during ESCs differentiation and downregulation of Notch-1 signaling could induce cardiogenesis in ESCs [ 23].
They induce proliferation and differentiation in a wide range of cells of epithelial, mesodermal and neuroectodermal origin (Basilico and Moscatelli 1992; Tanaka et al, 1992; Hu et al, 1998; Powers et al, 2000).
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As the word teratoid indicates, AT/RTs show the multiple-lineage developmental characteristics of malignant teratomas of neuroectodermal, mesodermal, and endodermal lineages [6], [13], [14].
In animal models, it has been shown that small increases in the levels of Sox2 expression (2-fold or less) could lead to rapid differentiation of epithelial stem cells into cells expressing neuroectodermal, mesodermal and trophectodermal markers [ 33].
However, the plasticity of MSC is not limited to mesenchymal derivatives, since MSC have been induced to differentiate into mesodermal, neuroectodermal and endodermal lineages [ 1].
A single copy number was present in tissues of different origins, such as mesodermal (joint cartilage and red bone marrow), endodermal (gastric mucosa and tonsils), ectodermal (coronary artery) and neuroectodermal (ischiatic nerve and medulla oblongata) derivatives, or those containing both endodermal and mesodermal components (bladder).
We measured the expression kinetics of three germ layer markers, Mash1 (neuroectodermal), Brachyury (early mesodermal) and Gata4 (endodermal), by quantitative real-time PCR (Q-PCR).
Related(18)
mesodermal and mesenchymal
mesodermal and hemogenic
mesodermal and endodermal
mesodermal and nonmesodermal
mesodermal and trophoblast
mesodermal and cardiovascular
mesodermal and pluripotent
mesodermal and septum
mesodermal and ectodermal
mesodermal and extraembryonic
mesodermal and mesectodermal
mesodermal and neurectodermal
mesodermal and cardiac
mesodermal and neuronal
mesodermal and epidermal
mesodermal and spinal
mesodermal and extra-embryonic
mesodermal and neural
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