Sentence examples for mediate this activity from inspiring English sources

This will require the identification of Nef determinants that specifically mediate this activity.

Even though it is established that the ESCRTs control tissue organization, the mechanisms that mediate this activity remain unclear.

Here we investigate the origins of one enzyme found in fungi, but not humans, that encodes the first reaction in the biosynthesis of leucine, and show that there are two distinct families of enzymes in fungi that mediate this activity.

This leads to decreased levels of K27me3 because the Polycomb repressive complex 2 which contains EZH2 is unable to mediate this activity in the presence of H3K27M [ 14].

It will be crucial now to determine the DNA-binding factors that mediate this activity and the effect that deleting these regions has on the expression and imprinting patterns of Kcnq1 and neighboring genes.

Transposon mutagenesis identified genes belonging to glycoside hydrolase (GH) 1, 3, or 5 as necessary for mediating this activity.

And the fact that there's a left and right signal gives me this feeling that I'm like the corpus callosum, mediating this activity between the two sides.

However, recombinant Cav1.2 channels expressed in COS1 cells establish functional coupling to CREB-dependent transcriptional activation [46], pointing to a physiologically relevant integration of recombinant Cav1.2 into a naturally occurring signaling cascade with Ca2+/calmodulin-dependent protein kinase II mediating this activity in native cells [47].

In such cases, one NLR acts as a pathogen 'sensor', and can contain a specific domain that mediates this activity, the second acts as an inducer of signalling.

In addition, we demonstrate that the bispecific single chain-Fv (bs-scFv) has intrinsic anti-cancer activity when measured in vitro and that the anti-ErbB3 arm of the bs-scFv is responsible for mediating this activity.

Nevertheless, the effect of family life on feces antimicrobial activities was absent with the four other tested microbial species, indicating that the compounds mediating this activity are fixed during the period of family life.