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However, the molecular intermediates that mediate this recognition remain obscure.
Since innate immune mechanisms are evolutionary designed to respond to a broad spectrum of pathological conditions, including cancer, applying the molecular mechanisms that mediate this recognition may help to develop new anti-tumor medicines.
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Many studies have demonstrated that individual animals can recognize one another as individuals and that, for mammals in particular, body volatiles (herein referred to loosely as odors) detected by olfactory or vomeronasal receptors play a prominent role in mediating this individual recognition [1].
Having demonstrated that SR-B1 can mediate the recognition of mycobacteria in transfected cells, we next investigated the contribution of this receptor on primary cells.
These receptors mediate the recognition of pathogen-associated molecular patterns (PAMPs) or damage-associated molecular patterns (DAMPs)—specific molecules released by damaged or necrotic cells [18, 19].
Finally, we expected that latencies under distracting stimuli would mediate the recognition in terms of target latencies and accuracy variables, depicting working memory (WM) and inhibition processes.
In yeast, several receptors (Tom70, Tom20 and Tom22) mediate the recognition of targeting sequences or internal information in the proteins being imported [34].
The first line of host defence against pathogenic organisms consists of surface-exposed pattern-recognition receptors that mediate the recognition of highly conserved microbial molecules [1] [2], termed pathogen-associated molecular patterns (PAMPs).
Many receptors and soluble ligands have been proposed to mediate the recognition and uptake of apoptotic cells.
The elicitors found in the oral secretions and regurgitants (OS) of the caterpillars enable plants to specifically recognize attack from insects; this recognition is mediated by complex signaling pathways in which jasmonic acid (JA) plays a central role [7], [8], [9].
This recognition is mediated by nodulation (Nod) factors, which are lipo-COSs with several functional group substitutions, including sulfation and fucosylation.
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CEO of Professional Science Editing for Scientists @ prosciediting.com