Therefore, this study was conducted to (1) determine the effects of Enz on migration, invasion, and in vivo metastasis; and (2) determine and implicate first molecular targets mediating this ability of Enz in NSCLC.
The brain systems mediating this integrative ability have been investigated using a wide range of experimental strategies.
Thus, further investigation is needed to identify the receptor or receptors that mediate the ability of intravenous administration of PACAP to trigger migraine-like headaches.
Other mechanisms or areas may also mediate the ability of GHS-R1A to regulate reward.
BslA mediates adhesion to host cells, and has been found to mediate the ability of the bacterium to cross the host blood-brain barrier.
Therefore, the chronic liver diseases may change the environment in vivo and mediate the ability of genetic factors to contribute to HCC.
We specifically pinpoint MSN and FN1 as well as TrkB as targets that can respectively mediate the ability of miR-200c to inhibit cell motility and anoikis resistance.
We demonstrated that inhibition of MSN and/or FN1 is sufficient to mediate the ability of miR-200c to suppress cell migration.
Ubiquitin ligases, such as Smurf2 and Arkadia, mediate the ability of TGF- β to induce ubiquitination and consequent degradation of SnoN [ 14].
This viral capsid mediates the ability of AAV vectors to overcome many of the biological barriers of viral transduction including cell surface receptor binding, endocytosis, intracellular trafficking, and unpackaging in the nucleus [6] [8].
