Sentence examples for mediate the dimerization from inspiring English sources

The TPM3 and TFG fusion partners contain dimeric α-coiled-coil structures that are hypothesized to mediate the dimerization of TPM3 ALK [ 121] and TFG ALK [ 119] respectively.

An SxxxA motif has been shown to mediate the dimerization of the TM region of ErbB2, while both GxxxG and SxxxS sequences have been implicated in TM dimerization.

(1– 3) These domains mediate the dimerization of striatin family members and the association with a diverse set of proteins, including calmodulin and caveolin.

Most selected sites lie in the loop between the two antiparallel alpha-helices and in the outer helix of the ankyrin module; even though none is directly involved in the 2′ 5′ oligoadenylates binding, they could potentially mediate the dimerization process or the interaction with other proteins.

Atomic structures of cadherin domains have led to a model for the cadherin adhesive interaction in which the membrane-distal extracellular domains mediate the dimerization of cadherins on the same cell and their attachment to the membrane-distal domains of cadherins from adjacent cells.

The electrostatic interactions between amino acids at position g and oppositely charged amino acids at position e' (the prime means a residue on the opposite helix of the leucine zipper) can form interhelical salt bridges which mediate the dimerization and determine the dimerization specificity as well as stability.

The N-terminal peptide of 153 residues in GmGT-2B was the minimal activation domain and the middle region between the two trihelices mediated the dimerization of the GmGT-2B.

The TFG coiled-coil domain plays an important role in TRK-T3 activation and its consequent biological activity insofar as it mediates the dimerization leading to the ligand-independent tyrosine phosphorylation of the TK domain.

Here, we report that c-di-GMP can assemble into a tetramer that mediates the effective dimerization of a transcription factor, BldD, which controls the progression of multicellular differentiation in sporulating actinomycete bacteria.

To define the molecular details that mediate the specificity of SNX-BAR dimerization and its role in membrane remodelling, we pursued the crystal structures of the SNX1 homodimer and SNX1 SNX5 heterodimer.

In the bacterial elements Tn10 and Tn5 synapsis is mediated by the dimerization of monomers bound to either end of the transposon.