Sentence examples for mediate the development from inspiring English sources

IL-12 is able to shift differentiation of CD4+ Th0 cells towards the Th1 phenotype [ 38], while IL-4 and IL-6 generally mediate the development of Th2 mediated diseases and regulate the Th1 responses by inhibition of interferon- γ (IFN- γ) production [ 39, 40].

Upon aberrant and chronic activation, myofibroblasts can mediate the development of fibrosis [16 20].

It argues that pre-existing socio-cultural processes mediate the development outcomes of energy access projects.

Cnidarians have many genes that mediate the development of tissues and organs, especially those of the mesoderm, the middle layer, in bilaterians.

These results demonstrate that in the pathophysiology of SGVHD, there is a redundancy in the TH17 effector molecules that mediate the development of SGVHD.

Therefore, the present study was designed to determine the degree to which DA receptors mediate the development of tolerance to the locomotor stimulant effects of caffeine.

These results suggest that FGF signalling mediates the development of the intermediate mesoderm, within which PGC precursors develop; therefore, we investigated the effects on PGCs by performing qRT-PCR on whole embryos.

These data support our hypothesis that both wild-type and dwarf fibroblasts develop age-associated sensitivity to ROT, but ROT mediated the development of this sensitivity is delayed in the dwarf fibroblasts.

Current evidence indicates that the acute locomotor stimulant effects of caffeine involve dopamine (DA) receptor activation; however, few studies have investigated the role of DA receptors in mediating the development of tolerance to caffeine.

Protein A is a well-characterized proinflammatory factor mediating the development of disease in the lung [23].

We used the same approach to test the hypothesis that STAT1 mediates the development of an aggressive pro-lung colonization phenotype as described here.