Sentence examples for facilitating the dimerization from inspiring English sources

The D-loop is also rotated away from the dimer interface, making the nucleotide-binding site of SufC more accessible and facilitating the dimerization of SufC for ATP binding and hydrolysis.

Upon binding of dsRNA, this autoinhibition is relieved facilitating the dimerization of two PKR molecules.

The increased ROS caused by NPGPx deficiency facilitated the dimerization of PKA regulatory subunits, leading to increased released of the PKA catalytic subunits and enhanced downstream signalling to activate C/EBPβ transcription.

These data led to the suggestion that DMF facilitated the slow dimerization of AMT (via the formation of a disulfide bond), and that the dimeric form of AMT served as an inhibitor for PDFEc.

Foreign double-stranded RNA (dsRNA), a by-product of viral RNA polymerases during virus replication, binds PKR, facilitates the homo-dimerization, auto-phosphorylation at Thr451 and Thr446, and thereby the activation of PKR (2, 3).

Furthermore, in MnmE, catalysis is facilitated by the dimerization of its G-domain [23].

AhR ARNT dimerization facilitates the conversion and transformation of the ligand AhR ARNT complex into its high-affinity DNA-binding form [ 22, 75].

It is possible that GT-4 dimerization may facilitate the association of GT-4 with TEM2, and whether this is the case remains to be further studied.

It will be interesting to determine whether LRP6 dimerization by antibodies or other extracellular agents facilitates the aggregation function of DVL, and whether coreceptor dimerization normally plays a functional role in Wnt signaling.

In addition, the lack of STAT1 phosphorylation by strongly in vivo activating TD mutations R248C and Y373C may stem from the fact that they affect the extracellular part of FGFR3 and activate FGFR3 by facilitating its dimerization [24].

Hence, the Mad1 C-terminal head and the RLK motif promote checkpoint function, but seemingly not through facilitating Mad2 dimerization.