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Our data also show that EMMPRIN up-regulated VEGFR-2 via HIF-2α, one of the isoforms of the hypoxia inducible factors that mediate adaptation to hypoxic stress in rapidly growing tissues such as tumors.

As a first example, two loci are predicted to mediate adaptation to anaerobic conditions.

Future studies should explore how bacterial diversity and function can mediate adaptation to high-energy diets and reduce disease risks.

The high frequency release of neuropeptides is in line with the ability to mediate adaptation to homeostatic challenges [ 23].

Given that PRC2-mediated H3K27me3 confers stemness and controls the development of organisms by regulating the expression of developmental genes, 66, 67) tumor cells might usurp this epigenetic process to mediate adaptation to tumor environments.

Overall, these data provide grounding for the theoretical study of how evolving stress tolerance affects population ranges in changing environments, and also suggest that more study is needed on how biotic interactions such as competition can mediate adaptation to environmental stress.

Similar(54)

A key mechanism of HVS for the global tone mapping is the mechanism of mediating adaptation to lighting conditions.

Recombination between internal repeats and chromosomal arms results in the accumulation of species-specific sequences, commonly mediating adaptation to the environment.

HIF-α is an oxygen-responsive transcription factor that mediates adaptation to hypoxia.

In line, we identified protein domains that are essential for mediating adaptation to iron starvation or iron excess, exclusively.

Interestingly the opening of a glycerol facilitator, belonging to the MIP family, mediates adaptation to hypo-osmotic conditions by the rapid release of intracellular glycerol [ 40].

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