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Alternatively, they may target proteins regulating the antibacterial response of macrophages.
Conversely, miRNAs that are distinctly upregulated in either oligodendrocytes or Schwann cells may target proteins and/or control processes that are specific to either PNS or CNS myelination.
Ubiquitination is a reversible posttranslational modification that may target proteins for degradation or coordinate signal transduction pathways [3, 4].
These data suggest that azithromycin and analogues are effective inhibitors of Plasmodium spp. merozoite and T. gondii tachyzoite invasion, raising the possibility that azithromycin may target proteins or events conserved between organisms.
Cysteine residues can be oxidized to intra- and inter-protein disulfides or reversibly over-oxidized to cysteine sulfenic acid, both of which are recovered by the actions of reductases; and they can be irreversibly oxidized to cysteine sulfinic and sulfonic acids, which impede protein function and may target proteins for degradation.
Similar(55)
We name this novel protein modification as DSSylation, in which DSS1 plays as a modifier, whose attachment may render target proteins a signature leading to their subsequent ubiquitination, thereby recruits proteasome to degrade them.
While fitting the model predictions to the experimental data from [ 33] we assumed that CaM may bind target proteins with different numbers of bound Ca2+ ions or even in the Ca2+ free state.
However, ubiquitination may not always target proteins for degradation.
The sub-network may include miRNAs, target proteins, proteins associated with target proteins and the associations between proteins.
Cocaine may target cytoskeleton proteins, particularly microtubule associated proteins (MAPs) [ 58] and actin filaments, altering the process of initiation, elongation, and turning of neuritic branches [ 59].
With the assumption that compounds with similar activity profiles may target similar proteins, new possible drug-protein interactions can be predicted by clustering analysis of compound bioactivity profiles across cell lines.
Related(20)
may identify proteins
may feature proteins
may include proteins
may miss proteins
may have proteins
may model proteins
may protect proteins
may target people
may reveal proteins
may express proteins
may sort proteins
may target students
may link proteins
may encode proteins
may secrete proteins
may involve proteins
may misregulate proteins
may help proteins
may target races
may allow proteins
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