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Alternatively, the recognition of novel motifs may link proteins previously thought to be unrelated e.g., suggesting a common function or interaction and therefore may aid in the determination of both structure and function for proteins that display the novel motif.
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Since cortactin operates mainly in cytoskeletal rearrangements, it may link other proteins via its SH3 domain to sites of actin polymerization.
The free cysteine residue in mature hG-CSF protein may link with the free cysteine residue of another hG-CSF protein through disulfide bonding to form a dimer.
This may link para-nucleolar DPR proteins to transcriptional changes induced by the expanded C9orf72 repeat DNA and RNA [ 20].
Therefore, this AS160 protein may link the pathways via which exercise and insulin stimulate glucose uptake.
To identify proteins that may link Lpd with regulators of endocytosis, we conducted a proteomic screen of a human fetal brain protein array with in vitro translated, S-labelled full length Lpd as the bait (Supplementary Figure S1A and B).
Our observations indicate the possibility of mechanisms that may link the pathogenesis of HSP proteins involved in ER morphogenesis and mitochondrial dysfunction.
The 3BP-1 protein may therefore be a mediator of SH3 function in transformation inhibition and may link tyrosine kinases to Ras-related proteins.
We hypothesized that sCD14 level increase may link to cytokine activation and protein-energy wasting, predisposing to increased mortality risk.
Thus, ERM-protein phosphorylation may link podoplanin expression to the observed rearrangement of the actin cytoskeleton.
It is reasonable to speculate that the changes of p-tau profiles in the brains of TSEs may link with the alternations of protein kinases.
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