Sentence examples for may affect phenotype from inspiring English sources

CNVs may affect phenotype through regulating gene's expression, such as the common CNV-loci for the gene PDPR [8], while most CNVs' deletion and amplification may not be consistent to the genes' down-regulation and over-expression.

That such mutations may affect phenotype is clear.

The distribution of AD pathology and associated atrophy varies among individuals [ 43] and may affect phenotype.

Remarkably, there have been almost no studies describing how environmental factors may affect phenotype in sarcomeric cardiomyopathies.

CNVs may affect phenotype by altering transcriptional level of genes within or adjacent to CNVR and subsequently alters translation levels.

CNVs may affect phenotype by altering transcriptional level of genes within or adjacent to CNVR and subsequently alter translation levels [ 60, 61].

Our current data support the hypothesis that a polymorphism in this gene may affect phenotypes that are dependent upon IGF1 function, at least in older black women.

As a fundamental form of genetic variation and the unit of inheritance, a haplotype may affect phenotypes either directly through influencing promoter activity and protein structure (Drysdale et al. 2000; Joosten et al. 2001) or indirectly through tagging nearby untyped causal variants (Clark 2004; Servin and Stephens 2007).

Non-synonymous variations are more likely to lead to functional mutations ('drivers') which may further affect phenotype.

Gene duplications may also affect phenotype by altering gene dosage: the amount of protein synthesized is often proportional to the number of gene copies present, so extra genes can lead to excess proteins.

These transcriptomic differences may in turn affect phenotype.