It suggests that additional factors may control the phenotypes of SP cells.
Given that miRs coordinately regulate the complex webs of cardiac gene networks and that DHD is associated with altered gene expression, it is tempting to speculate that these 'micro' elements may control 'macro' phenotypes in diabetic heart.
These results suggest that the FZD activating event accumulation may contribute to enhance the activity of the downstream pathways that may control the cancerous phenotype.
Because of the divergent correlations between DN progression and mortality with family history, we speculate that different genetic variants may control these two phenotypes.
This finding confirms our hypothesis that a subset of Car-R−derived cancer-resistance alleles may control two cancer phenotypes in the backcross population.
In agreement with previous findings (Saran et al. 2002), lung tumor multiplicity and skin papilloma multiplicity had a weak but significant correlation (Pearson's coefficient = 0.20, P = 0.003), supporting the idea that a subset of loci may control both lung and skin tumor phenotypes.
This implies that a post-transcriptional method of regulation may control the transition from the DNA synthesis and growth phenotype of 24hr liver stage parasites to the cytokinesis and merozoite formation phenotype of 48hr liver stage parasites.
The efficiency of activating latent transforming growth factor (TGF -β1 in sysTGF -β1upus erythematosus (SLE) may control the balance between inflammation and fibrosystemiculupusg therythematosusnotype.
However, while histone PTM may be strongly correlated with epigenetically controlled phenotype, there is no evidence that any histone PTM is causal to transgenerationally inherited risk.
This reduces the number of integrants needed to screen for loss of gene function and may enable genes controlling phenotypes in mammalian cells to be isolated.
