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Body composition may affect chemotherapy tolerance and toxicities.
Certain tumor characteristics have been related to poor prognosis and may affect chemotherapy decision among stage II colon cancer [ 5].
The heterogeneity of head and neck tumors in combination with HPV infection may cause complex molecular perturbations in the cell and differences in survival and migration pathways that are affected may affect chemotherapy or radiation resistance and therefore prognosis of HPV-positive vs. HPV-negative SCCHN.
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High CXCR4 expression may affect the chemotherapy drug reaction in metastatic renal cancer.
These macrophages may affect sensitivity to chemotherapy.
These specific macrophages play an important role in the tumour microenvironment and may affect sensitivity to chemotherapy [ 16].
Recent efforts have concentrated on understanding how co-amplification of HER2 with the non-core amplicon gene Topoisomerase II (TOP2A) may affect response to chemotherapy (Pritchard et al, 2008).
Closer assessment of these samples revealed they were obtained from post-chemotherapy tissues, suggesting chemotherapy may affect RUNX2 expression.
We believe that guidelines for monitoring cardiotoxic reactions in patients given anthracycline chemotherapy should account for patient age, cumulative Dox dose, and the risk that a false-positive result may affect the choice of chemotherapy.
This may affect the clearance of chemotherapy drugs leading to increased toxicity or ineffectiveness 17.
There is a growing body of evidence that chemotherapy may affect the outcomes of patients with resectable gastric cancer (Carrato et al, 2005).
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