Sentence examples for master regulator gene from inspiring English sources

The master regulator gene studied by Dr. Ruvkun's team is called daf-16 in worms and FOXO in mammals.

MyoD, recognised as a master regulator gene for skeletal muscle differentiation27, was constructed as the tetracycline-inducible MyoD piggyBac vector (Tet-MyoD) (Fig. 1a).

Albeit the mechanism is unknown, several lines of evidence indicate that spermidine functions by modulating the transcriptional expression of the master regulator gene exsA.

The promoter-lacZ fusion reporter systems of several key T3SS genes, including the master regulator gene exsA, the effector genes exoS and exoT, have been previously exploited for screening and characterization of regulatory genes [26], [29].

In general, the presence of eQTL hotspots suggests either the presence of a master regulator gene which controls the expression of groups of genes together or the presence of several tightly linked genes within the hotspot, each of which regulates the expression of a subset of genes mapping to this locus [31], [33], [34].

To determine whether disruption of the spermidine transporter may have a pleiotropic effect on the type III secretion machinery, the master regulator gene exsA was cloned under the control of the lac promoter in plasimd vector pDSK519 to generate the expression construct pDSK-exsA.

A question of interest for biologists studying cell identity is what regulates the master regulator genes.

The Fox genes are a large family of master regulator genes that control other genes.

The Broad team then looked at the chromatin state of the master regulator genes in several kinds of mature cell.

All the genes in question, though, act in a similar way — they are master regulator genes whose role is to turn other genes on or off.

They found it had sought out some 200 sites where many of the master regulator genes of human cells are located.