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This is a myeloproliferative disease characterized by marked increase in granulocytes, marked bone marrow hyperplasia and spleenomegaly (2).
Further, if MRI reveals marked bone marrow oedema at the calcaneal origin of the PF in patients with plantar fasciitis, a concomitant enthesopathy of the Achilles tendon should be suspected [4].
Joints from the vehicle-treated CIA group exhibited significant damage as well as swelling of soft tissues and marked bone marrow edema.
Lastly, adenoviral overexpression of COMP-Ang1 in mice exposed to total body irradiation prevented marked bone marrow hypocellularity and apoptosis, thereby preventing IR-induced myelosuppression [ 34].
In the same study, the mortality of the Abcc10-knockout mice was found to be significantly increased due to neutropenia and marked bone marrow toxicity after paclitaxel treatment [13].
In the same study, Mrp7 knockout mice exhibited higher lethality associated neutropenia and marked bone marrow toxicity upon treatment with paclitaxel, indicating that Mrp7 is indispensable for health and viability.
Similar(43)
Dashed lines mark bone marrow (bm), compact bone (cb), growth plate (gp) and metaphyseal (mp) bone regions.
This study suggests that nestin-CreERT marks bone marrow MSCs that have both self-renewal and multilineage potential in vivo.
At this time a fixed complement of 10 7) congenically marked donor bone marrow cells B6-Gpi-1a-->B6-Gpi-1b B6-Gpi-1a-->B6-Gpi-1b B6-Gpi-1a-->B6-Gpi-1b B6-Gpi-1a-->B6-Gpi-1b B6-Gpi-1a-->B6-Gpi-1b B6-Gpi-1a-->B6-Gpi-1b B6-Gpi-1a-->B6-Gpi-1b
This enhancement was much more marked with bone marrow-derived RA-NLCs compared with synovium-derived RA-NLCs.
There is currently no FDA-approved therapy for fibrosing diseases, and so, a better understanding of fibrocytes and their regulation marks these bone marrow-derived progenitors as potential therapeutic modalities to not only augment normal wound healing, but also potentially reverse fibrosis in many disease states.
Related(16)
labeled bone marrow
labelled bone marrow
distinguish bone marrow
substantial bone marrow
remarkable bone marrow
marked bone resorption
marked bone absorption
marked bone expansion
marked bone formation
marked bone demineralisation
marked bone damage
marked bone loss
marked bone proliferation
marked bone erosion
marked bone reaction
marked bone destruction
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