Sentence examples for many pathogenic processes from inspiring English sources

In any case, there is abundant literature demonstrating the importance of ribosomal biosynthesis and oxidative metabolism involving mitochondria and the Warburg effect in many pathogenic processes including carcinogenesis [1], [44], [45].

In a previous gene expression study using brain tissue samples from cattle experimentally infected with BSE, we have demonstrated that the largest number of differentially regulated genes is detected at 21 months post inoculation, suggesting that there are many pathogenic processes in the animal brain even prior to the detection of infectivity in the CNS of these orally dosed cattle [11].

As many pathogenic processes remain uncharacterized, the fraction of genes involved in pathogenesis may be larger than we could interpret.

Motivation: Deregulated signaling cascades are known to play a crucial role in many pathogenic processes, among them are tumor initiation and progression.

The rapidity of microglia activation following a variety of neurological insults and the sensitivity of this process to even subtle changes in addition to its implication in many pathogenic processes prompts the in vivo imaging of microglia activation with TSPO.

This goal may be facilitated by the fact that the many distinct pathogenic processes associated with stroke, trauma, and neurodegenerative diseases appear to converge on several mutually reinforcing final common pathways: excitotoxicity by excess glutamate receptor stimulation, intracellular calcium overload, oxidative stress, mitochondrial failure, and apoptosis.

Many pathogenic and physical processes including ischemia connect with ROS.

Reactive oxygen species (ROS) play key roles in many physiologic and pathogenic processes.

eATP promotes many of the pathogenic processes resulting in calcium crystal deposition and OA in cartilage.

A number of studies have suggested that differences between the two types are not always straightforward, and in many cases, common pathogenic processes may be evident (5).

Finally, highly reactive unsaturated aldehydes (e.g., acrolein, 4-hydroxy-2-nonenal) are also generated endogenously during the oxidative stress associated with many pathogenic and toxicogenic processes.