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Although CNB domain-containing proteins have been identified in many pathogenic organisms, an incomplete understanding of how CNB domains in pathogens differ from other eukaryotic hosts has hindered the development of selective inhibitors for CNB domains associated with infectious diseases.
Terpenoid precursor biosynthesis occurs in human and many pathogenic organisms via the mevalonate and 2-C-methyl-d-erythritol-4-phosphate (MEP) pathways, respectively.
Exocyclic olefin variants of thymidylate (dTMP) recently have been proposed as reaction intermediates for the thymidyl biosynthesis enzymes found in many pathogenic organisms, yet synthetic reports on these materials are lacking.
Genome sequencing and bioinformatics have provided the full hypothetical proteome of many pathogenic organisms.
In this context of diversity it is remarkable that so many pathogenic organisms appear to bind and adhere to fibronectin (Fn) substrates.
The flagellum is implicated in an ever growing spectrum of human genetic disease [15] and is an attribute of many pathogenic organisms.
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Since recently, many human pathogenic organisms have been recognized to exist on plant root or leaf surfaces (Lyytikainen et al., 2004; Brandl, 2006), and even inside plant tissues (Kutter et al., 2006; Rosenblueth and Martínez-Romero, 2006).
In infants who developed NEC, the prominence of many potentially pathogenic organisms is striking.
Drug resistance is known in many pathogenic micro-organisms, as well as in larger parasites.
Now outbreaks involve larger populations and may be multistate and even international; in many the pathogenic organism has a low infective dose and sometimes is never isolated from the food product.
Over the past decade, the genomes of many of these pathogenic organisms have been sequenced, revealing unexpected diversity in genome sizes and overall genome organization.
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many infectious organisms
many disease organisms
many pathogenic pathways
many pathogenic microorganisms
many pathogenic mutations
many pathogenic actions
many pathogenic diseases
many pathogenic protozoa
many pathogenic microbes
many thermophilic organisms
many pathogenic states
many pathogenic agents
many different organisms
many pathogenic bacteria
many pathogenic fungi
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