Sentence examples for manner without altering from inspiring English sources

The results indicate that TCDD decreases progesterone, androstenedione, testosterone, and estradiol levels in a non-monotonic dose response manner without altering growth of antral follicles.

Interestingly, we further observed that, although NSC23925 directly inhibits the function of Pgp1 in a dose-dependent manner without altering the total expression level of Pgp1, NSC23925 actually stimulates ATPase activity of Pgp, a phenomenon seen in other Pgp inhibitors.

In this way, the diversification of individual regulatory elements allows expression to be modulated in a tissue– and/or temporal specific manner without altering gene function.

Viruses (HIV-1AD8 and HIV-1J6363) were increasingly bound to and internalized in Caco-2 cells in a time-dependent manner without altering the integrity of the monolayer (Fig 9A, and Fig S9 of Supporting Information).

The two main types of epigenetic mechanisms are DNA methylation and histone modifications, which work together to affect gene expression in a potentially heritable manner (without altering DNA sequence) and influence chromatin structure (9– 11).

The results showed that both aspirin and indomethacin inhibited cell growth and induced apoptosis of AGS cells in a dose- and time-dependent manner, without altering the cell cycle.

28, 33, 34 As a result, the LBPP treadmill technology is gaining popularity as a device that offers the ability to study weight-supported or low-load exercise in a user-friendly and kinematically correct manner, 28, 35 without altering gait dynamics 28 or cardiovascular parameters such as heart rate and blood pressure.

PD98059 blocked glial cell line-derived neurotrophic factor-induced PC12-GFRα1 cells neurite formation in a dose-dependent manner, without significantly altering cell viability.

Because epigenetic processes are major regulators of gene expression, these findings suggest that dysregulation of epigenetic processes could contribute mechanistically to arsenic-induced changes in gene expression and cancer, affecting both people exposed to arsenic directly and those of future generations in a heritable manner, without directly altering the genome.

More importantly, only in our work is data presented suggesting that serotonin may act in a cell-type selective manner; increasing proliferation of β cells, or their progenitors, without altering δ cell numbers.

Strobilopterus princetonii γ meanwhile resolves as the sister taxon to Strobilopterus proteus and Strobilopterus princetonii without altering the rest of the tree in any manner.