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Cells can adapt to environment and development by reconstructing their transcriptional networks to regulate diverse cellular processes without altering the underlying DNA sequences.
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On basis of the quantum calculations and photophysical data, we conclude that the carbazole moieties effectively reduce the intermolecular interaction by enhancing the steric hindrance of the complex, which inhibits the quenching process without altering the nature of the excited-state.
Taken together, our findings point to the interesting likelihood that reduced genomic methylation activity adversely affects the healthy aging process without altering survival and mortality.
When presented uniformly, FGFs similarly lead to a significant lengthening of Tie1+ process outgrowth (Fig. 4S) without altering the number of DAPI+ cells, or M-phase cells within [CAMv] explants (Fig. 4T,U; supplementary material Table S2).
(pp 282 291) Processes that modify gene expression without altering the underlying DNA sequence (i.e., epigenetic processes) contribute to a person's predisposition to alcoholism, report Mr. Bela G. Starkman and Drs. Amul J. Sakharkar and Subhash C. Pandey.
Epigenetic processes that modify the genome without altering the genetic sequence may also play a role by affecting gene expression.
"We are going over the rules for generics to debureaucratize the process as much as possible without altering the technical requirements that guarantee the effectiveness and security of the drugs," said Mauricio Vianna, general manager for prescription drugs at the National Agency of Sanitary Vigilance, or Anvisa, the government regulatory agency.
Through exploring the integration of these data into each of the stages of SEA under the EPBC Act, we show that opportunities exist to strengthen the effectiveness of SEA in delivering conservation outcomes without altering existing legal processes.
Thus, the microencapsulated broccoli could be easily added to processed foodstuff increasing their healthy properties without altering their sensory attributes.
They built their new computer chip in facilities used to mass-produce the ones inside our laptops and mobile devices without altering the manufacturing process at all.
Remarkably, these GFP variants exhibited little to no loss in specific fluorescence activity relative to GFPmut2, suggesting that the process of superfolding can be accomplished without altering the proteins' normal function.
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