Sentence examples for major regulatory pathways from inspiring English sources

The T3SS of Ech3937 is regulated by two major regulatory pathways, the HrpX/HrpY-HrpS-HrpL and the GacS/GacA-rsmB-RsmA pathways [15], [16].

Moreover, the ADCY2 encoding protein regulates the intracellular levels of cyclic AMP, a crucial second messenger in major regulatory pathways involved in the biogenesis of the genital system such as Sonic Hedgehog signaling.

In the present study, we have characterized the spermatogenic phenotypes in CF mice model, which reveals that defects of CFTR cause dysregulation of the major regulatory pathways in spermatogenesis, such as CREB in Sertoli cells and CREM in germ cells, resulting in impaired sperm production.

The following paragraphs summarize the major regulatory pathways regulating autophagy in these settings.

10.7554/eLife.00947.008 Figure 3. Recapitulation of the major regulatory pathways for autophagy by in vitro lipidation of T7-LC3.

Thus, for endogenous and recombinant LC3, the cell-free reaction reflects and responds to the major regulatory pathways of autophagy.

The Kelch-like ECH-associated protein 1 (Keap1)–nuclear factor erythroid 2 p45-related factor 2 (Nrf2) system is a major regulatory pathway of cytoprotective genes against oxidative and electrophilic stress.

A large amount of evidence has suggested that platelet-derived growth factor B (PDGF-B /PDGFRβ signaling functions as the major regulatory PDGF-B /PDGFRβerning pericyte recruitment (Bell et al., 2010; Daneman et al., 2010; signalingt al., 2016; Chen et al., 2017).

Another major regulatory pathway is RNA inhibition.

The loss of such a major regulatory pathway could promote tumourigenesis and provide an explanation for an increased risk of developing prostate cancer while having little effect on outcome once cancer has developed [17].

The DC-SIGN receptor (dendritic cell-specific ICAM3-grabbing non-integrin) acts as a major regulatory pathway [ 111].