Sentence examples for important regulatory pathways from inspiring English sources
The PI3K/AKT/mTOR signaling pathway is one of the most important regulatory pathways of cell growth and survival in healthy and cancerous cells, as evidenced by the finding that alterations in this pathway are one of the most common in human cancers (Mayer & Arteaga, 2016; Zhang et al., 2017).
Still, these changes add or remove a considerable amount of genetic material and are probably to cause a spillover effect to important regulatory pathways.
CDK11p58 is involved in a variety of important regulatory pathways in eukaryotic cells, including cell cycle control, apoptosis, neuronal physiology, differentiation and transcription [ 26– 28].
CDK11p58 is involved in a variety of important regulatory pathways in eukaryotic cells, including cell cycle control, apoptosis, neuronal physiology, differentiation and autophagy [ 10, 27– 31].
The retinoblastoma (RB -E2F pathway is one of the most impoRB -E2Fegulatory pathways that control and couple cell disisioneand cell differentiatiof [ 2, 3].
The backbone network derived from high BC proteins presents a clear and visual overview which shows all important regulatory pathways for blood pressure (BP) and the crosstalk between them.
The conservation among species suggests that miRNAs represent a relatively old and important regulatory pathway [54].
Nonetheless, taken together, these observations depict the Nampt-Sirt6 axis as an important regulatory pathway for cytokines involved in inflammation and cell-mediated immunity, that could be blocked with FK866 or, possibly, with Sirt6 inhibitors (Figure 9).
The most important regulatory pathway in maintaining cholesterol homeostasis is therefore reverse cholesterol transport (RCT).
IRF5 is regulated by type I IFN, indicating an important regulatory pathway for the controlled induction of multiple immunomodulatory genes.
Overexpression of HAC1, the most direct control for UPR genes, resulted in significant new understanding of this important regulatory pathway in P. pastoris, and generally in yeasts.
