Sentence examples for primary regulatory pathways from inspiring English sources

There are 2 primary regulatory pathways of autophagy: MTOR (mechanistic target of rapamycin), a negative regulator, and PtdIns3K (class III phosphatidylinositol 3-kinase), a positive regulator.

Hypoxia-inducible factor is considered to be one of the primary regulatory pathways involved in hypoxia tolerance (Wang and Semenza 1993).

Many of these factors make a minor contribution to the involution process, however, either because of redundancy or because they are not essential components of the primary regulatory pathways.

The mammalian target of rapamycin (mTOR) and PI3K (phosphoinositide 3-kinase)/Akt, serine/threonine kinase, [also named protein kinase B (PKB)] pathways are considered primary autophagy regulatory pathways and are extensively researched [ 11, 12].

By correlating metabolite profiles of Arabidopsis thaliana plants grown in varying K conditions with transcript profiles and post-translational enzyme activities we identified specific changes in primary metabolic and regulatory pathways that occur upstream and downstream of the observed changes in sugar levels [ 2].

To gain an insight into the pattern of genes or gene regulatory pathways allowing the primary tumours to metastasise to the lymph nodes, we selected genes that were significantly expressed in both primary tumour and lymph node metastasis of one patient as computed by the Rosetta error model (P<0.01) (Hughes et al, 2000; van 't Veer et al, 2002).

Defensin expression may have been put under imd pathway control to fight Gram-positive bacterial infections in barrier epithelia in which the imd, and not the Toll, pathway appears to play a primary regulatory role [32], [33].

Our aim was to define patterns of genes or gene regulatory pathways that drive the metastatic dissemination of primary breast cancer cells to the lymph nodes.

Sirt3, a member of the family, functions mainly as the primary mitochondrial deacetylase that modulates mitochondrial metabolic and oxidative stress regulatory pathways [ 9, 13, 14].

It suggests potential human APP gene regulatory pathways, not on the basis of comparing DNA primary sequences with zebrafish appb but on the model of conservation of transcription factors.

This suggests that infecting EBV triggers cellular changes by de-regulating many factors in signal transduction or regulatory pathways in order to remain in its host after primary infection.