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The major pathogenesis of PD is its loss of DA neurons, thus making it a good candidate for cell therapy.
The major reason is that the prokinetics do not improve or even impair gastric accommodation that is one of the major pathogenesis of gastroparesis and functional dyspepsia [ 84].
At the time of this discovery, a substrate for WNK kinases was yet to be identified, but it was expected that NCC was regulated by WNK1 and WNK4 because the activation of NCC was considered the major pathogenesis of PHAII.
The major pathogenesis of T2DM is insulin resistance, which is the resistance of target tissues to insulin action, and has been suggested to play a key role in the cluster of diabetic complications including atherosclerosis, and diabetic nephropathy (DN) [ 2, 3].
Focal or disseminated vasculitis is the major pathogenesis of complications following scrub typhus. 1 Scrub typhus can lead to the involvement of various intra-abdominal organs. 1 However, the pathogenesis of splenic infarction associated with scrub typhus has not been previously documented, and splenic complications such as splenic infarction may be extremely rare and underreported. 1, 2.
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Epigenetics plays a major role in the pathogenesis of the major psychoses.
Epigenetic mechanisms are thought to play a major role in the pathogenesis of the major psychoses (schizophrenia and bipolar disorder), and they may be the link between the environment and the genome in the pathogenesis of these disorders.
Stress induced by the events of daily life is considered a major factor in pathogenesis of primary tension-type headache.
In our study, patients with IL-6 rs1800795 CC genotype had higher risk of septic shock-related death, suggesting that IL-6 rs1800795 polymorphism may play a major role in pathogenesis of septic shock.
Bacterial endotoxins (lipopolysaccharides (LPS)) play a major role in pathogenesis of Gram-negative sepsis.
T cells also play a major role in pathogenesis of SLE.
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