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Finally the primary pathogenesis of COPD is characterized by lung inflammation and there is increasing data about the role of inflammation in the development of cancer [95].
The underlying concept is that once the primary pathogenesis of diabetes is established, hyperglycemia and very commonly hyperlipidemia ensue and thereafter exert additional damaging or toxic effects on the β-cell [7].
Deficiency of kidney qi is known to be the primary pathogenesis of UI according to 'ZhuBingYuanHouLun' (a famous ancient TCM literature).
The role of the placenta in the primary pathogenesis of the disorder indisputably indicates a fetal contribution to susceptibility to the disorder.
AGEs have been implicated in the primary pathogenesis of diabetic vascular damage that ultimately leads to progressive vascular occlusions, as in diabetic maculopathy.
Recent studies have determined that the predomination of IgA plasma cells within mucosal surfaces is a common characteristic of many of the infectious diseases of childhood, as well as KD [ 8, 16, 17], which suggests that an immune response in a genetically susceptible patient following exposure to a pathogen represents the primary pathogenesis of KD.
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Our results, therefore, indicate that autoantibodies to ZnT8 are a downstream event to the primary genetic pathogenesis of type 1 diabetes.
Our results support the notion that lung epithelial cells are involved in initiating hypercytokinemia [ 9], which is a primary component of pathogenesis of VN1203.
Perhaps it is the hypoxia that may underlie endothelial dysfunction, a primary stage of pathogenesis of vascular disorders, and the impact on this stage of the disease will let us improve the results of treatment of patients with VD.
The stereotypic response in acute gout is consistent with the recurrent paroxysmal nature of the disease and the primary role in pathogenesis of 'professional phagocytes', unlike the case for inflammation driven by adaptive immune responses [ 10].
Primary pulmonary choriocarcinoma is an extremely rare entity and the pathogenesis of primary pulmonary choriocarcinoma has not been established yet.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com