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Immune-mediated liver injury is an important pathogenesis of HBV infection.
Several lines of evidence now suggest that the ischemia of organs after trauma or severe sepsis would be the most important pathogenesis of MODS [ 5, 6].
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Nef is an important pathogenesis factor of HIV-1 with a multitude of effector functions.
We speculate these previously difficult to detect interactions in cells are likely to be important to pathogenesis of polyglutamine diseases.
PAI-1 also seems to be important in pathogenesis of renal diseases.
Minisatellite instability appears far less important in pathogenesis of lung cancer.
Moreover, it cannot provide enough information on the environmental factors that are important for pathogenesis of certain diseases.
The GalU gene has also been found to be important for pathogenesis of e.g. Pseudomonas aeruginosa and Francisella tularensis [ 50– 50].
This may be important in the pathogenesis of salpingitis.
Monocytes/macrophages, proinflammatory cytokines and chemokines are important in the pathogenesis of glomerulonephritis.
Impaired hippocampal function is believed to be important in the pathogenesis of depression.
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