Sentence examples for major developmental pathways from inspiring English sources

Runx genes are key regulators of lineage-specific gene expression in major developmental pathways.

Moreover, RXR/RAR heterodimer action is enhanced by histone deacetylase inhibitors, promoting major developmental pathways in pluripotent cells [37].

In contrast, genes from major developmental pathways (e.g. fibroblast growth factor, wingless), although present on the array, were largely unaffected in fogsk8 embryos (Supplementary Table S3).

Wnt signaling is one of the major developmental pathways, evolutionarily conserved in all animals (Logan & Nusse, 2004).

To date, three major developmental pathways were shown to be involved with gonad differentiation through the modulation of programmed cell death.

RUNX3 is a known regulator of major developmental pathways, and has recently been reported as a candidate tumor suppressor [ 3- 5].

A cytological analysis showed that two modes of Brussels sprouts microspore embryogenesis exist: a direct route via embryos which was the major developmental pathway, and an indirect route via calli.

Classical studies in Drosophila highlighted the role of Hox genes as major developmental pathway switches leading to a traditional view of these transcriptional factors acting as selector genes [13], [21], [30].

The WNT signalling pathway is a major developmental pathway that is involved in cell fate, differentiation and proliferation.

Therefore, coupling of a bona fide neurotransmitter and drug receptor, such as CB1R, to this major developmental pathway may open interesting research and therapeutic perspectives.

Given the strong enrichment of genes associated with Signalling Pathways and Development and Differentiation functions (Tables  3 and 4), we sorted DE genes according to participation in major developmental regulatory pathways.