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BMP1/TLL genes are widely expressed and have major developmental roles in early embryogenesis [ 16].
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The homozygous offspring is viable in a Mendelian ratio (Table 2), suggesting that GRASP65 does not have a major developmental role during embryogenesis.
Genetic analyses of Drosophila NRs have identified their role in controlling major developmental transition and maturation (King-Jones and Thummel, 2005).
Classical studies in Drosophila highlighted the role of Hox genes as major developmental pathway switches leading to a traditional view of these transcriptional factors acting as selector genes [13], [21], [30].
These studies dramatically expand the known roles of SDF1α-Cxcr4 signalling to encompass almost every major developmental program of cerebellar development.
This represents a clear example of the relationship between microhabitat structure and evolution of a major developmental and life history trait, and has broad implications for the role of localized ecological conditions on larger-scale evolutionary processes.
Current Controlled Trials ISRCTN95538913 Mid to late adolescence constitutes a phase of major developmental changes and age-specific demands associated with the biographic transition into a more adult role [ 1- 3].
Nelken has a successful portfolio career working with arts funders, creative producing and developmental roles.
As Free Software has evolved and matured over the years, several major developmental archetypes have emerged.
For a study targeting children, major developmental tests have been conducted.
Moreover, their relatively small cost permits to rapidly implement a prototype design without major developmental constraints.
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