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Exact(5)
Because the majority of studies have focused on detecting major developmental abnormalities at a very young age, still little is known about the milder difficulties children may experience in the long run.
In C. elegans, fzy-1 (h1983) did not exhibit major developmental abnormalities, except for the smaller brood size [20].
Deficiencies in specific Dbl proteins usually do not induce major developmental abnormalities as revealed by studies with mice knock-out for specific Rho GEFs, even though in a few cases lack of GEFs can cause embryonic lethality and/or association with abnormal development.
An extensive workup failed to demonstrate any other major developmental abnormalities.
While no major developmental abnormalities were observed, after recurrent seizures we detected neuronal loss, mossy fibre sprouting, astrocyte reactivity and granule cell dispersion in the hippocampus of LGI1−/− mice.
Similar(55)
Genomic imbalances are a major cause of congenital and developmental abnormalities including dysmorphic features, mental retardation and developmental delay, and multiple congenital anomalies.
No dysmorphisms or congenital abnormalities or major developmental delay have been reported.
The major cause of spontaneous miscarriage is genetic or developmental abnormalities of the fetus.
The major cause of spontaneous miscarriage is genetic or developmental abnormalities of the foetus.
Analysis of mRNA expression patterns in early embryos via cDNA microarray technology would provide insights into the function of gene regulatory networks and would thus be a major step forward in unravelling molecular mechanisms underlying developmental abnormalities.
These effects on gene expression parallel the growth delay and developmental abnormalities including brain, neural tube, eye, heart, blood cells, and embryonic vascularization which are major targets in FASD.
More suggestions(15)
major congenital abnormalities
major echocardiographic abnormalities
major developmental milestones
major developmental differences
major developmental processes
major developmental delays
major autosomal abnormalities
major developmental stages
major developmental pathways
major vascular abnormalities
major developmental changes
major developmental constraints
major developmental transitions
major developmental questions
major genetic abnormalities
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