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Exact(14)
Carboxylate anion groups are the major binding sites in wool [20] and silk [23].
For three of the Fab libraries, the CDR regions appeared as major binding sites for all multimodal ligands.
The major binding sites on DNA and their binding affinities toward the surfactant (DTAB) are identified by Fourier Transform InfraRed (FTIR) spectroscopy.
Earlier crystallographic and ensuing SAR studies have revealed that the active site of NA could be divided into four major binding sites [28].
The selectivity displayed by the synthesised model compound 2 towards Cu2 + ions ascertained the participation of pyridine N′s of DPA as the major binding sites.
These results indicate that Atf1 and Pcr1 share their major binding sites in the genome, consistent with previous studies on individual genes [22].
Similar(46)
All NLSs bind to the major binding site, spanning armadillo repeats 1 4, and some also have a small additional contribution from the minor site, spanning repeats 6 8.[ 8] TPX2, however, binds primarily to the minor site of importin-α, thereby offering an opportunity for selectivity.
Studies have shown that the N-terminal "KR" motif of bipartite NLSs binds the P1' and positionsiofs of the minor binding site in importin α, while the larger "KRRK" motif binds the P2 P5 positions of the major binding site in importin α [36] (Fig. 8A).
Although CGG repeats constitute a major binding site for CGGBP1, there are CGG-free regions to which it binds.
Secondly, the "major" binding site between PN2 and PC1 is of a more extended conformation in the access and binding phases, but contracts in the extrusion phase (with a relative rotation of 21°) essentially eliminating the substrate binding.
Thus, the entire substrate-transport path (including the entrance cleft, "major" binding site, and exit cleft) is formed between the two units, PN1-PC2 and PN2-PC1 (Li et al. 2015) (Fig. 2D).
Related(20)
principal binding sites
main binding sites
tremendous binding sites
primary binding sites
important binding sites
large binding sites
broad binding sites
major publishing sites
major blog sites
major phosphorylation sites
major cleavage sites
major binding patterns
major binding interactions
major pilot sites
major binding patches
major binding forces
major tourist sites
major binding saccharides
major news sites
major tube sites
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