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For example, the homeoprotein CRX (cone rod homeobox), which itself is expressed predominantly in photoreceptors, binds to the consensus sequence C/TTAATCC/A and has functionally important binding sites present in the upstream region of many photoreceptor-specific genes, including rhodopsin, arrestin, IRBP, and β-phosphodiesterase-6 [19], [24], [24].
NS3h contains two important binding sites: the NTPase binding site and the RNA binding site.
Based on previous findings, we hypothesized that the complementarity-determining regions (CDRs) constitute important binding sites for multimodal chromatographic ligands.
According to this finding, Asp86 and Lys89 residues were important binding sites.
30 Guanines are also the most important binding sites for platinum II) complexes, such as trinuclear BBR3464.
Likewise, the loose conformation of the highly conserved regions of sequence suggests that these may represent important binding sites for transregulatory elements.
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The PABP-interacting motif PAM2 has been identified in various eukaryotic proteins as an important binding site for the PABC domain.
Moreover, the region is also located proximal to another important binding site.
This indicates that Lys292 may be an important binding site for Asc.
The results suggest that the positive charge of the Arg299 guanidinium group may be an important binding site for Asc.
Hence, the analysis indicated HIF1 as the most important binding site in two of the gene sets.
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