Sentence examples for maintain their differentiation from inspiring English sources

In tissue engineering it is important that the scaffold allows cells to attach, spread, maintain their differentiation status or differentiate into functional cells in order to exhibit their physiological function.

Moreover, cell polarity appeared well preserved on this substrate, so polarized cells like hepatoma HepaRG cells might maintain their differentiation status and act as primary human hepatocytes for hepatotoxicity testing.

These results suggest that Ker-CT-Ras keratinocytes maintain their differentiation expression profile irrespective of their randomized location, but that subsequent modifications alter the cellular expression profile.

Localized NKX3.1-mediated TNFα-JNK signaling in prostate epithelial cells may promote and maintain their differentiation state thus suppressing tumorigenesis.

These data show that isolated hAMSCs maintain their differentiation potential when grown in serum-free M5 medium.

Nevertheless, the ability of many neuroblastoma cell lines to maintain their differentiation capability in vitro has made them suitable models for studying human neuronal differentiation.

The cells exhibited high metabolic activity, responded to growth factor stimuli and maintained their differentiation status.

Thus, the main aim of our study was to develop biocompatible and biodegradable MCs that can support high MSC yields while maintaining their differentiation capability and potency.

Together with clonogenic culture conditions, FGF-2 supplementation prolongs the life span of bone marrow stromal cells to more than 70 doublings and maintains their differentiation potential until 50 doublings.

These hES cell derived hepatic progenitor cells could maintain their proliferation capacity for more than 100 days of culture in vitro, while maintaining their differentiation potential into both hepatocyte-like and cholangiocyte-like cells.

In addition it is now clear in the literature that growth of hMSCs at low oxygen tensions maintains their differentiation capacity[50], [58], which may be due to a reduction in oxidative stress induced aging [5].