Sentence examples for retaining their differentiation from inspiring English sources

Placing the inner cell mass in vitro under the finely tuned culture conditions prevents their imminent differentiation and allows cells to self-renew seemingly indefinitely whilst retaining their differentiation potential (Thomson et al., 1998).

Alternative differentiation is observed in human keratinocytes lacking p16INK-4a, expressing telomerase and retaining their differentiation capacities (N-hTERT cells) upon sublethal repeated exposures to UVB [7].

Repeated exposures to sublethal doses of UVB induce an alternative differentiation state rather than premature senescence in cultivated human keratinocytes lacking functional p16INK-4a, immortalized with telomerase and retaining their differentiation capacities (called N-hTERT cells herein) [7], [8].

The upscaled WJ-MSCs retained their differentiation potential and immunosuppressive capacity.

However, the surviving cells were able to retain their differentiation potential; and this is demonstrated for the adipogenic lineage.

To overcome this problem, we attempted to prolong the life span of human placenta-derived mesenchymal cells (hPDMCs) by modifying hTERT and Bmi-1, and investigated whether these modified hPDMCs retained their differentiation capability and multipotency.

We demonstrated that young MSCs retained their differentiation potential (measuring adipogenic differentiation; data not shown), but that HBO had no effect on this process.

Mad was strongly expressed in differentiating suprabasal keratinocytes in healing dermal wounds and in benign hyperproliferative conditions, but also in squamous cell carcinomas, in which the keratinocytes retain their differentiation potential.

As pluripotency and tumorigenesis have commonly been considered a packaged deal, it is imperative to consider what factors allow Muse cells to avoid tumor formation while retaining their capacity for differentiation into all three germ lineages.

Mouse ES cells undergo unlimited self-renewal in the presence of the cytokine LIF, while retaining their multi-lineage differentiation capacity.

Embryonic stem (ES) cells have the remarkable capacity to divide indefinitely while retaining their wide range differentiation potential, and they represent a promising source for cell transplantation therapies [1].