Sentence examples for main regulatory elements from inspiring English sources

Although the TLR4 promoter region has no direct STAT3 binding site, its PU.1 binding site is considered to be one of its main regulatory elements and STAT3 has been shown to be capable of activating PU.1 [51].

We focused on the above region because it is the control region of the mtDNA, it contains the main regulatory elements for its replication and expression and it is the most rapidly evolving region of this genome.

In this experimental population, p3_VvAGL11 and VMC7F2 explain up to 78% of the phenotypic variation in seedless, which make them very good candidates for being the main regulatory elements involved in the expression of the final seedless phenotype.

Thus, we identified nuclear FAK binding partners that can interact, directly or indirectly, with five of the six main regulatory elements reported to control transcription of Ccl5 in multiple cell types (Fessele et al., 2002).

The high level of similarity in the organisation and gene content of the 3′ end of the bovine, murine and human TRA/TRD loci, which contains the TRAJ, TRDJ, TRAC, TRDC genes and the main regulatory elements, indicates that since the divergence of the primate, rodent and artiodactyl lineages 100 million years ago (MYA) [ 29] there has been strong conservative evolution of this region.

The main regulatory element responsible for the expression of Sox2 in pluripotent stem cells is located ∼4 kb downstream of the single Sox2 coding exon and it is named SRR2 (Sikorska et al., 2008; Tomioka et al., 2002).

We found that the main cis-regulatory elements described for polyadenylation are a strong, and highly informative, hallmark for constitutive sites only.

Our analysis demonstrated that the main cis-regulatory elements described to be responsible for polyadenylation, are a strong and in fact a highly informative hallmark for constitutive sites only.

As noted earlier, the main cis-regulatory elements responsible for polyadenylation are located in the flanking region (−40,+40) nt from polyA sites, while further downstream and/or upstream (−100,+100) of the polyA site lie some other G/U-rich segments of sequences, with varying length, location and exact sequence compositions.

The three main Ensembl classification types, excluding regulatory elements, for regions that overlap CNVs are protein-coding genes (76 %), pseudogenes (11 %) and multiple classes of RNAs (10%%).

More and more comparative genomics programs are being demanded to identify protein-coding genome regions, placement of regulatory elements, and the main evolutionary dynamics affecting the complexity of genome organization.