Sentence examples for main regulatory molecules from inspiring English sources

In this review, we provide the main regulatory molecules that govern the main basic mechanisms, extrinsic and intrinsic, of apoptosis in normal cells.

We have used IHC to determine expression levels in breast tumours of the main regulatory molecules of the eIF4E pathway – namely, eIF4E, 4E-BP1, 4E-BP2 and phosphorylated 4E-BP1 (termed46) (termed p4E-BP1).

Here, we provide an overview of mechanisms by which the main regulatory molecules govern apoptosis in normal cells and describe models of apoptotic dysregulation based on alterations in their function that facilitate the evasion of apoptosis in cancer cells.

In fact, stimulation of HUVECs with all three main known regulatory molecules of the tip cell phenotype, i.e. VEGF [ 3], TNF-α [ 39], and Notch ligand DLL4 [ 4], resulted in an increase or decrease of CD34+ cells in HUVEC cultures as predicted by our hypothesis.

Calcium is the main regulatory and signalling molecule in muscle and ATP synthesis is dependent on phosphate transport.

The previously described process of muscle plasticity is closely linked with, and highly dependent on, calcium metabolism and transport, as muscles use calcium ions as their main regulatory and signaling molecule.

However, several of the main transcription factors and known regulatory molecules of early B cell differentiation were either not affected or rather expressed at a slightly higher level in the BCS-derived EPLMs.

Lung development is driven by two forces: intrinsic factors that include a host of regulatory molecules and extrinsic forces, the main one being extracellular lung fluid [ 63].

The rationale for this diversity of regulatory molecules in different bacteria is that synthesis of ADP-Glc is strictly regulated by the main metabolic pathways operating in the respective organism [ 1].

A set of autophagy regulatory molecules was identified by genetic screening in yeast, particularly autophagy (Atg -related proteins, which Atg -related proteinsin autophagy.

Generally, rRNA P1 promoters are considered to represent the main regulatory target for ppGpp, yet the P2 promoters have also been shown to respond to changes of the effector molecule, although less dramatically [ 30- 32].